The information provided on this site is intended only
for healthcare professionals (HCPs) in the United States.
Are you an HCP?
THYQUIDITY is designed for consistent daily
administration of any medically appropriate dose1
With THYQUIDITY, your patients or their caregivers can administer
the prescribed dose individualized to their TSH goal
- THYQUIDITY is a liquid oral solution with 100 mcg levothyroxine sodium per 5 mL (20 mcg per mL)
- THYQUIDITY is supplied in a package of two 100 mL bottles. Based on the average daily dose, 1 prescription of THYQUIDITY should last an adult patient ~6 weeks. A bottle of THYQUIDITY can be used up to 8 weeks once opened*
Calibrated oral syringe provided by pharmacy.
- THYQUIDITY is drawn from the bottle into a calibrated oral syringe provided by the pharmacy and administered directly into the mouth
- Taken once daily on an empty stomach one half to one hour before breakfast
- Administered at least 4 hours before or after drugs that are known to interfere with absorption
*Assuming the strength of levothyroxine sodium prescribed daily is 88 mcg (4.4 mL). With two 100 mL bottles included in a package of THYQUIDITY, it would take a patient ~45 days to finish.2
T4: thyroxine; TSH: thyroid-stimulating hormone.
A liquid formulation designed to deliver an individualized dose to patients1
Patient type
Starting dose†
Dose adjustment‡ and TSH measurement
Patient type
Otherwise healthy, nonelderly individuals who have been hypothyroid for only a short time (a few months)Starting dose†
1.6 mcg/kg/dayDose adjustment‡ and TSH measurement
Adjust by 12.5 to 25 mcg increments every 4 to 6 weeks until clinically euthyroid and TSH normalizedPatient type
Elderly patients or patients with underlying cardiac diseaseStarting dose†
12.5 to 25 mcg/dayDose adjustment‡ and TSH measurement
Increase dose every 6 to 8 weeks until clinically euthyroid and TSH normalizedPatient type
Patients with severe, long-standing hypothyroidismStarting dose†
12.5 to 25 mcg/day Dose adjustment‡ and TSH measurement
Adjust by 12.5 to 25 mcg increments every 2 to 4 weeks until clinically euthyroid and TSH normalizedPatient type
Pediatric patientsStarting dose†
See Prescribing Information for age-specific dosing guidelines from age 0 to completion of pubertyPatient type
Pregnant patients with pre-existing primary hypothyroidismStarting dose†
THYQUIDITY dose requirements may increase during pregnancy. Measure serum TSH and free-T4 as soon as pregnancy is confirmed and, at a minimum, during each trimester of pregnancy. Maintain serum TSH in the trimester-specific reference rangePatient type
Pregnant patients with new-onset hypothyroidismStarting dose†
Normalize thyroid function as rapidly as possible. Evaluate serum TSH every 4 weeks and adjust THYQUIDITY dosage until serum TSH is within the normal trimester-specific range Patient type
Patients with well-differentiated thyroid cancerStarting dose†
Generally, TSH is suppressed to below 0.1 mIU per liter, and this usually requires a THYQUIDITY dose of >2 mcg/kg/day. However, in patients with high-risk tumors, the target level for TSH suppression may be lower
Microgram to milliliter conversion: mcg x 0.05 = mL or total mcg/20 = total mL of THYQUIDITY
Example: 60 mcg = 3.0 mL
†Starting dose depends on a variety of factors, including age, body weight, cardiovascular status, and concomitant medical conditions (including pregnancy), concomitant medications, coadministered food, and the specific nature of the condition being treated.
‡Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect THYQUIDITY absorption.
T4: thyroxine; TSH: thyroid-stimulating hormone.
Please see the Prescribing Information for additional guidelines for dosing in specific patient populations.
Broad dosing flexibility
As a liquid, THYQUIDITY can help you meet patients’ individual
needs with flexible dosing adjustments1
Starting dose calculator for adults.
Levothyroxine dosing conversion by weight.
Starting dose calculator.
Levothyroxine tablet (mcg) to liquid (mL) conversion.
Healthy nonelderly adults (growth and puberty complete)
who have been hypothyroid for a short time (a few months)
Enter your patient’s
weight in pounds
Enter the desired
dose in micrograms
Refer to full Prescribing Information for dosing guidance at this weight.Refer to full Prescribing Information for dose guidance at this amount.
Recommended starting dose based on patient weight (1.6 mcg/kg).
Doses greater than 200 mcg per day are seldom required.
An inadequate response to daily doses of greater than 300 mcg per day is rare and may indicate poor compliance, malabsorption, drug interactions, or a combination of these factors.
- Starting dose depends on a variety of factors, including age, body weight, cardiovascular status, and concomitant medical conditions (including pregnancy), concomitant medications, coadministered food, and the specific nature of the condition being treated. Peak therapeutic effect may not be attained for 4-6 weeks
- Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect THYQUIDITY absorption
- Adequacy of therapy is determined with periodic monitoring of TSH and/or T4 levels, as well as clinical status
RESOURCES AND SUPPORT
View materials and programs available to patients taking THYQUIDITY
